Purpose: To provide an in-depth exploration of the potential benefits, mechanisms, and practical considerations of using Nimodipine, a calcium channel blocker, for managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Key Points: Drug Overview: Nimodipine is a second-generation L-type calcium channel blocker, primarily used to improve blood flow in the brain by relaxing blood vessel walls. It…
Purpose: To shed light on the profound challenges faced by individuals with Severe/Very Severe Myalgic Encephalomyelitis (ME), emphasizing the physical nature of the illness and the need for accurate understanding and support. Key Points: Misinterpretation of Symptoms: Severe ME symptoms are often dismissed or misinterpreted as psychological due to their invisibility and complexity. Terms like…
Purpose: To explore the historical misrepresentation of Myalgic Encephalomyelitis (ME) as merely “fatigue,” highlighting the scientific evidence that supports its classification as a chronic neurological disease. Key Points: Origins of Misrepresentation: ME was historically dismissed as “fatigue syndrome,” overshadowing the broader neurological symptoms such as muscle pain, cognitive issues, and impaired circulation. Lack of understanding…
Purpose: To highlight the groundbreaking research on B-cell depletion therapy for severely affected Myalgic Encephalomyelitis (ME) patients, emphasizing the potential benefits, clinical findings, and future research directions. Key Points: Accidental Discovery: Norwegian oncologists, Dr. Øystein Fluge and Professor Olav Mella, observed “major symptom relief” in a cancer patient with severe ME undergoing chemotherapy. This led…
Purpose: To establish that Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a physical disorder, countering efforts to classify it as a psychiatric or behavioral condition. Key Points: WHO and Official Recognition: The WHO confirmed in 2014 that ME/CFS is not classified as a mental or behavioral disorder in ICD-10 or proposed for ICD-11. The UK government…
Purpose: To discuss the clinical features, potential causes, and management strategies for Myalgic Encephalomyelitis (ME), emphasizing the importance of early rest and understanding of the condition. Key Points: Clinical Features: ME often follows a viral infection and presents with persistent fatigue, muscle weakness, headaches, blurred vision, and neurological symptoms such as difficulty concentrating and memory…
Purpose: To examine the long-term impacts of Myalgic Encephalomyelitis (ME), its parallels with Post-Polio Syndrome, and the need for improved recognition, research, and management strategies. Key Points: Nature of ME: ME is a chronic neurological illness caused by enteroviral infections, leading to multi-system impacts, including skeletal, cardiac, and endocrine organ damage. Symptoms include overwhelming fatigue,…
Purpose: To examine the long-term impacts of Myalgic Encephalomyelitis (ME), its parallels with Post-Polio Syndrome, and the need for improved recognition, research, and management strategies. Key Points: Nature of ME: ME is a chronic neurological illness caused by enteroviral infections, leading to multi-system impacts, including skeletal, cardiac, and endocrine organ damage. Symptoms include overwhelming fatigue,…
Purpose: To outline the historical context, research developments, and modern advancements in understanding how persistent enteroviral infections contribute to chronic neurological diseases like ME (Myalgic Encephalomyelitis). Key Points: Historical Context: Early 20th-century research identified non-paralytic poliomyelitis linked to neurological issues. Advances, such as the discovery of Coxsackie viruses, demonstrated how non-polio enteroviruses could affect neurological…
Purpose: To explore the origins, increasing prevalence, clinical features, and management of Myalgic Encephalomyelitis (ME/CFS), addressing its paradoxical rise in “affluent” communities. Key Points: Origin and Nature of ME/CFS: ME/CFS is a neurological disorder often triggered by viral infections and was historically linked to non-paralytic poliomyelitis. Increases in ME/CFS were observed following the decline of…