Purpose This page explains the key issues that arise when Myalgic Encephalomyelitis (M.E.) and Chronic Fatigue Syndrome (CFS) are treated as the same condition. It highlights how broad diagnostic criteria can lead to misdiagnosis, confusion in research, and inappropriate clinical care. Key Points 1. Core Problem Broad fatigue-based criteria (such as Fukuda) group together different…
Purpose This page provides an overview of the core symptoms of Myalgic Encephalomyelitis (M.E.), based on early clinical observations and descriptions. It aims to outline the key features of the condition, highlight its complex and fluctuating nature, and support understanding of its neurological and systemic impact. Key Points 1. Core Clinical Features M.E. was originally…
Purpose This page provides an overview of perceptual and sensory dysfunctions in Myalgic Encephalomyelitis (M.E.). It explains the types of symptoms patients may experience, their underlying neurological causes, and practical strategies to reduce their impact. Key Points 1. Nature of Perceptual and Sensory Dysfunction Problems processing sensory information and maintaining spatial awareness Difficulty interpreting and…
Purpose This page explains vivid dreams and nightmares as a recognised symptom of Myalgic Encephalomyelitis (M.E.) under the International Consensus Criteria (ICC 2011). It outlines how these experiences relate to neurological and sleep dysfunction within the illness, and why they are part of the disease process rather than simply psychological in origin. Key Points 1….
Purpose This page explains the cognitive impairments associated with Myalgic Encephalomyelitis (M.E.) as defined by the International Consensus Criteria (ICC 2011). It outlines the nature of these symptoms, their underlying causes, and practical strategies for managing them in daily life. Key Points 1. Core Cognitive Impairments Slowed information processing and reduced thinking speed Difficulty finding…
Purpose This page explains what an M.E. “crash” is, based on the International Consensus Criteria (ICC 2011). It outlines what triggers a crash, the wide range of symptoms involved, and why this response is a defining biological feature of the disease—not simply fatigue. Key Points 1. What is an M.E. Crash A crash is caused…
Purpose This page provides a clear overview of the long-term and cumulative effects of Myalgic Encephalomyelitis (M.E.). It explains how the illness can progress over time, affecting multiple systems in the body, and highlights the importance of recognising severity and supporting appropriate long-term care. Key Points 1. Progressive Nature of M.E. M.E. can worsen over…
Purpose This page provides a clear and direct explanation of the differences between Myalgic Encephalomyelitis (M.E.) and Chronic Fatigue Syndrome (CFS). It aims to reduce confusion, improve understanding, and support better diagnosis and management. Key Points 1. Core Difference M.E. is a specific neuroimmune disease characterised by systemic dysfunction CFS is a broad syndrome primarily…
Purpose Persistent disequilibrium is a significant and under-recognised symptom in Myalgic Encephalomyelitis (ME). This page explains what it is, why it happens, how it differs from other conditions, and how it can be managed safely and effectively. What Persistent Disequilibrium Feels Like Patients commonly report: A constant sense of imbalance (rocking, swaying, or internal motion)…
Purpose To summarize the discussions and outcomes of two All-Party Parliamentary Group (APPG) meetings on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), emphasizing key topics and stakeholder concerns. Key Points February 2007 Meeting Guest speakers included representatives from NICE, who addressed the development of draft guidelines on ME/CFS. Concerns were raised over the “blanket recommendation” of CBT…